If interested in participating or learning more,
please click on the Get In Touch button to answer
a few screening questions and provide us with contact information.

Join a
48-month healthy lifestyle
program for
overweight
women

Research study for women with little to
no knee pain. Participants will also receive
financial compensation.

For over 30 years, our international research team has conducted successful weight loss studies. Our team is now conducting The Osteoarthritis Prevention Study (TOPS). We are looking for women to enroll in a 48-month healthy lifestyle program.

Osteoarthritis is the leading cause of disability in women over the age of 50. By studying women with little to no knee pain, our goal is to identify measures that can be taken to prevent the onset of this debilitating condition.

Study sites include Wake Forest University, UNC-Chapel Hill, Brigham and Women’s Hospital, and the University of Sydney.

The study sponsors include the National Institutes of Health, the Arthritis Foundation, CDC, Wake Forest University and Rapid Nutrition.

Why Participate?

• Enroll in a free 48-month Healthy Lifestyle Program
  
• Receive sessions that may include a combination of weight loss, healthy lifestyle, nutrition, and exercise
  
• Receive up to $140
  
• Receive free medical tests (knee x-ray and MRI)
  
• Contribute to research and potentially impact future osteoarthritis treatments and prevention strategies
  
  

What is Involved?

Participants will be randomly assigned to one of two Healthy Lifestyle Programs lasting 48 months.

Diet & Exercise Program

• Follow a low-calorie personalized diet, with the goal of losing 10% of your body weight
  
• Diet will include up to 2 meal replacements per day (these are provided by the study and are optional - similar to Slim Fast powder supplements)
  
• Exercise classes 2 days a week
  
• Exercise instructors will monitor progress and help participants reach their fitness goals

Healthy Living Program

• Attend 4 group classes each year for 4 years with a focus on nutrition, physical health, mental health, and other health topics
  
• Receive monthly contacts from the study team via newsletters and text messages with additional health information

Eligibility

Candidates may be eligible to participate if they…

• Are female and 50 years of age or older
  
• Are overweight
  (BMI of 30 kg/m2 or higher)
  
• Have little to no knee pain

TOPS Study Phone: 1-877-238-4825, option 6                            TOPS Study Email: tops@wfu.edu      

Join a 48-month healthy lifestyle program for overweight women

Research study for women with little to no knee pain. Participants will also receive financial compensation.

TOPS Study Phone: 1-877-238-4825, option 6

TOPS Study Email: tops@wfu.edu

For over 30 years, our international research team has conducted successful weight loss studies. Our team is now conducting The Osteoarthritis Prevention Study (TOPS). We are looking for women to enroll in a 48-month healthy lifestyle program.

Why Participate?

• Enroll in a free 48-month Healthy Lifestyle Program
  
• Receive sessions that may include a combination of weight loss, healthy lifestyle, nutrition, and exercise
  
• Receive up to $140
  
• Receive free medical tests (knee x-ray and MRI)
  
• Contribute to research and potentially impact future osteoarthritis treatments and prevention strategies
  
  

What is Involved?

Participants will be randomly assigned to one of two Healthy Lifestyle Programs lasting 48 months.

Diet & Exercise Program

• Follow a low-calorie personalized diet, with the goal of losing 10% of your body weight
  
• Diet will include up to 2 meal replacements per day (these are provided by the study and are optional - similar to Slim Fast powder supplements)
  
• Exercise classes 2 days a week
  
• Exercise instructors will monitor progress and help participants reach their fitness goals

Healthy Living Program

• Attend 4 group classes each year for 4 years with a focus on nutrition, physical health, mental health, and other health topics
  
• Receive monthly contacts from the study team via newsletters and text messages with additional health information
  
  

Eligibility

Candidates may be eligible to participate if they…

• Are female and 50 years of age or older
  
• Are overweight
  (BMI of 30 kg/m2 or higher)
  
• Have little to no knee pain

If interested in participating or learning more, please click on the Get In Touch button to answer a few screening questions and provide us with contact information.